Compounds > etravirine
Page last updated: 2024-09-05

etravirine and 4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide

etravirine has been researched along with 4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide in 2 studies

Compound Research Comparison

Studies
(etravirine)		Trials
(etravirine)		Recent Studies (post-2010)
(etravirine)		Studies
(4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide)		Trials
(4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide)		Recent Studies (post-2010) (4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide)
5729032128015

Protein Interaction Comparison

ProteinTaxonomyetravirine (IC50)4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide (IC50)
Cytochrome P450 2C9 Homo sapiens (human)0.19
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1371
5-hydroxytryptamine receptor 4Homo sapiens (human)0.483

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Chen, FE; De Clercq, E; Huang, WJ; Jin, X; Pannecouque, C; Wang, S; Zhang, YX; Zhao, LM1
Chen, FE; Clercq, E; Hao, QQ; Ling, X; Pannecouque, C1

Other Studies

2 other study(ies) available for etravirine and 4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide

ArticleYear
Structure-Based Discovery of Novel NH
    Journal of medicinal chemistry, 2022, 06-23, Volume: 65, Issue:12

    Topics: Anti-HIV Agents; Biphenyl Compounds; Drug Design; Heterocyclic Compounds, 1-Ring; HIV Reverse Transcriptase; HIV-1; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2022
Expansion of the S-CN-DABO scaffold to exploit the impact on inhibitory activities against the non-nucleoside HIV-1 reverse transcriptase.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Animals; Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Mice; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2022